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Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is often a Vietnamese traditionally medicinal plant utilized in treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to research the results of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the highest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (with the exception of total flavonoids) and antioxidant capacity, when compared to conventional and ultrasound-assisted extractions. These data demonstrate that the usage of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application inside the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly modify the phytochemical compounds and biological activity from plant materials. The aims on this study could determine the consequences of different drying methods, various solvents and extraction methods on the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root purchased from Vietnam. The outcomes indicated that microwave drying was a highly effective method in elimination of water when it comes to shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity in the P. trimera root while methanol and microwave-assisted extraction were the most effective solvent and means for greatest extraction in the phytochemical compounds and antioxidant capacity in the P. trimera root. The findings because of this study allow retaining the very best degrees of phytochemical compounds and antioxidant capacity in the P. trimera root for potential application in the nutraceutical industry.

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